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SMG1 (gene)
Serine/threonine-protein kinase SMG1 is an enzyme that in humans is encoded by the ''SMG1'' gene.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=23049 )〕 SMG1 belongs to the phosphatidylinositol 3-kinase-related kinase protein family. == Function ==
This gene encodes a protein involved in nonsense-mediated mRNA decay (NMD) as part of the mRNA surveillance complex. The protein has kinase activity and is thought to function in NMD by phosphorylating the regulator of nonsense transcripts 1 protein. Alternative spliced transcript variants have been described, but their full-length natures have not been determined.〔
抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「SMG1 (gene)」の詳細全文を読む
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